Homework 14: Fill in the blank – 3 points each entry – capitalization does not matter. Students can take this assignment an unlimited number of times with the best score kept.
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1. Question
This exercise is a continuation of analysis on the gene expression analysis of lung adenocarcinoma and matched adjacent non-tumor lung tissue dataset (NCBI identifier: GSE32863) from NCBI’s Gene Expression Omnibus (GEO). To save time, the relevant information from the series matrix file and the platform file have been combined and provided in the attached text file. Use this file as input to iDEP and use the Network tab results to answer the following questions:
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A network of ____ genes was divided into ___ modules.
How many genes are included in the turquoise module (#1)?
After selecting the blue module (#2), list the three gene symbols shown in the network in alphabetical order.
After selecting the yellow module (#4), what is the network’s centralized gene symbol?
After selecting the entire network, how many enriched pathways among all genes were listed?
After selecting the entire network, how many differentially active pathways found from GO Biological Process have adjusted p-value 1.6e-21?
After selecting the entire network, how many genes contributed to enrichment of the cell migration pathway?
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